Hi, I am Xefjord and studying Geopolitics and playing Strategy games is a pretty big hobby of mine. The recent developer update really highlighted a lot more of the nation/node building mechanics and the empires that could spawn from them, so I thought I would take a crack at looking at the pixelated new map to try to make some geographic conclusions as to where the best regions for empire building could be.
I know that Steven said that there won't be a single best node for creating empires, and I do agree with him. Geopolitics is a balance between Geography, Demographics, and Resources. The latter two factors we can't really predict yet. But that doesn't change the fact there will be some regions blessed to have less Geographic obstacles than others, and we can make guesstimations regarding the demography and resource density of certain regions based on their biomes, topography, and access to trade with the outside world through safe ocean paths and riverways.
I have created a map with my hypothesis on what will be the best regions in the world for Empire development, which ones will be challenging, and which ones will be incredibly difficult. I have also labeled the map with numbers so we can better discuss specific regions. I want this to be an open discussion where people can give their input so the Devs can see where the community thinks the best spots will be to settle, and also so maybe we can tweak the map a little for balancing. Feel free to ask me any questions regarding my Hypothesis down below and why I labeled certain regions the way I did.
Here is my hypothesis (old, but keeping for reference to older posts):

Here is my most recent hypothesis linked below factoring in demographic assumptions from starting zones: